Intrathecal serotherapy in neonatal tetanus: a controlled trial.
نویسندگان
چکیده
منابع مشابه
Intrathecal serotherapy in neonatal tetanus: a controlled trial.
60 infants with neonatal tetanus were treated at random either by 40 000 units of equine tetanus antitoxin (TAT), intravenously and intramuscularly, or by 40 000 units TAT, IV and IM, plus 150 units of human tetanus immune globulin TIG) intrathecally. There were 30 infants in each treatment group. Babies were similar in age, sex, weight, incubation period, temperature, and signs and symptoms on...
متن کاملIntrathecal anti-tetanus human immunoglobulin in the treatment of neonatal tetanus.
OBJECTIVE To determine the outcome of tetanus in neonates treated with intrathecal tetanus immunoglobulin in terms of mortality and hospital stay. STUDY DESIGN Experimental study. PLACE AND DURATION OF STUDY Paediatric Unit I, Bahawal Victoria Hospital, Bahawalpur, from April 2004 to December 2007. METHODOLOGY Seventy neonates with diagnosis of neonatal tetanus were included in the study....
متن کاملRandomised controlled trial of tetanus treatment with antitetanus immunoglobulin by the intrathecal or intramuscular route.
OBJECTIVE To evaluate the effect of intrathecal therapy with human antitetanus immunoglobulin on clinical progression of and mortality from tetanus. DESIGN Randomised controlled trial. SETTING Intensive care unit of a university hospital, Pernambuco, Brazil. PARTICIPANTS 120 patients with tetanus allocated to antitetanus immunoglobulin by either the intrathecal and intramuscular route (n ...
متن کاملA randomized double-blind sham-controlled study of intrathecal human anti-tetanus immunoglobulin in the management of tetanus.
BACKGROUND Tetanus is a major cause of mortality and morbidity in developing countries. Various modalities of treatment to prevent progression of the disease and alter its outcome have been tried. This study was designed to evaluate the role of intrathecal human anti-tetanus immunoglobulin (TIG) in the management of tetanus. METHODS Thirty-six adult patients presenting to an university-affili...
متن کاملNeonatal tetanus in Casablanca
Neonatal tetanus (NT) remains common in developing countries. Its poor prognosis is characterized by a high mortality rate. Patients and methods – Our retrospective review concerned 50 cases of NT admitted to the intensive care and neonatology units in the Casablanca Children’s Hospital between 1990 and 1999. The diagnosis was made on clinical signs and gravity was evaluated with the Dakar scor...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1979
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.54.8.623